1. Simões R V, Muñoz-Moreno E, Cruz-Lemini M, Eixarch E, Bargalló N, Sanz-Cortés M, Gratacós E. Brain metabolite alterations in infants born preterm with intrauterine growth restriction: association with structural changes and neurodevelopmental outcome. Am J Obstet Gynecol. 216(1), 62.e1-62.e14 (2017).

2. Benkarim OM, Sanroma G, Zimmer VA, Muñoz-Moreno E, Hahner N, Eixarch E, Camara O, González Ballester MA, Piella G. Toward the automatic quantification of in utero brain development in 3D structural MRI: A review. Hum Brain Mapp. 38(5):2772-2787 (2017).

3. Zimmer VA, Glocker B, Hahner N, Eixarch E, Sanromaa G, Gratacós E, Rueckert D, González Ballester MA, Piella G. Learning and combining image neighborhoods using random forests for neonatal brain disease classification. Medical Image Analysis. 42(2017):188-189 (2017).

4. Padilla N, Fransson P, Donaire A, Figueras F, Arranz A, Sanz-Cortés M, Tenorio V, Bargallo N, Junqué C, Lagercrantz H, Ådén U, Gratacós E. Intrinsic Functional Connectivity in Preterm Infants with Fetal Growth Restriction Evaluated at 12 Months Corrected Age. Cereb Cortex. 27(10):4750-4758 (2017).

5. Sanz Cortes M, Bargallo N, Arranz A, Simoes R, Figueras F, Gratacos E. Feasibility and Success Rate of a Fetal MRI and MR Spectroscopy Research Protocol Performed at Term Using a 3.0-Tesla Scanner. Fetal Diagn. Ther. 41(2):127-135 (2017).


1. Baños N, Perez-Moreno A, Migliorelli F, Triginer L, Cobo T, Bonet-Carne E, Gratacos E, Palacio M. Quantitative Analysis of the Cervical Texture by Ultrasound and Correlation with Gestational Age. Fetal Diagn. Ther. 41(4):265-272 (2017).

2. Baños N, Murillo-Bravo C, Julià C, Migliorelli F, Perez-Moreno A, Ríos J, Gratacos E, Valentin L, Palacio M. Mid-trimester sonographic Cervical Consistency Index to predict spontaneous preterm birth in a low-risk population. Ultrasound Obstet Gynecol. [2017 Epub ahead or print].

3. Cobo T, Munrós J, Ríos J, Ferreri J, Migliorelli F, Baños N, Gratacós E, Palacio M. Contribution of Amniotic Fluid along Gestation to the Prediction of Perinatal Mortality in Women with Early Preterm Premature Rupture of Membranes. Fetal Diagn Ther. [2017 Epub ahead or print].

4. Baños N, Perez-Moreno A, Julià C, Murillo-Bravo C, Coronado D, Gratacos E, Deprest J, Palacio M. Quantitative analysis of the cervical texture by ultrasound in the mid-pregnancy is associated with spontaneous preterm birth. Ultrasound Obstet Gynecol. [2017 Epub ahead or print].

5. Palacio M, Bonet-Carne E, Cobo T, Perez-Moreno A, Sabrià J, Richter J, Kacerovsky M, Jacobsson B, García-Posada RA, Bugatto F, Santisteve R, Vives À, Parra-Cordero M, Hernandez-Andrade E, Bartha JL, Carretero-Lucena P, Tan KL, Cruz-Martínez R, Burke M, Vavilala S, Iruretagoyena I, Delgado JL, Schenone M, Vilanova J, Botet F, Yeo GS, Hyett J, Deprest J, Romero R, Gratacos E,Fetal Lung Texture Team. Prediction of Neonatal Respiratory Morbidity by Quantitative Ultrasound Lung Texture Analysis: A Multicenter Study. Am J Obstet Gynecol. 217(2):196.e1-196.e14 (2017).

6. Palacio M, Caradeux J, Sánchez M, Cobo T, Figueras F, Coll O, Gratacós E, Cararach V. Uterine Cervical Length Measurement to Reduce Length of Stay in Patients Admitted for Threatened Preterm Labor: A Randomized Trial. Fetal Diagn Ther. [2017 Epub ahead or print].

7. Caradeux J, Murillo C, Julià C, Escura S, Ferrero S, Cobo T, Gratacós E, Palacio M. Follow-Up of Asymptomatic High-Risk Patients with Normal Cervical Length to Predict Recurrence of Preterm Birth. Fetal Diagn Ther. [2017 Epub ahead or print].

8. Berghella V, Palacio M, Ness A, Alfirevic Z, Nicolaides KH, Saccone G. Cervical length screening for prevention of preterm birth in singleton pregnancy with threatened preterm labor: systematic review and meta-analysis of randomized controlled trials using individual patient-level data. Ultrasound Obstet Gynecol. 49(3):322-329 (2017).


1. Cobo T, Vives I, Rodríguez-Trujillo A, Murillo C, Ángeles MA, Bosch J, Vergara A, Gratacós E, Palacio M. Impact of microbial invasion of amniotic cavity and the type of microorganisms on short-term neonatal outcome in women with preterm labor and intact membranes. Acta Obstet Gynecol Scand. 96(5):570-579 (2017).

2. Rodríguez-Trujillo A, Ríos J, Ángeles MA, Posadas DE, Murillo C, Rueda C, Botet F, Bosch J, Vergara A, Gratacós E, Palacio M, Cobo T. Influence of perinatal inflammation on the neurodevelopmental outcome of premature infants. J Matern Fetal Neonatal Med. 1-221 (2017).

3. Cobo T, Palacio M, Grande M, Sánchez-García AB, Estanyol JM, López M, Bosch J, Martí C, Gratacós E. Cervical Alpha-Actinin-4 Is Upregulated in Women with Threatened Preterm Labor and Microbial Invasion of the Amniotic Cavity. Fetal Diagn Ther. [2017 Epub ahead or print].

4. Cobo T, Kacerovsky M, Jacobsson B. Noninvasive Sampling of the Intrauterine Environment in Women with Preterm Laborand Intact Membranes. Fetal Diagn Ther. [2017 Epub ahead or print].

5. Polettini J, Cobo T, Kacerovsky M, Vinturache AE, Laudanski P, Peelen MJCS, Helmer H, Lamont RF, Takeda J, Lapointe J, Torloni MR, Zhong N, Menon R. Biomarkers of spontaneous preterm birth: a systematic review of studies using multiplex analysis. J Perinat Med. 45(1), 71–84 (2017).

6. Kacerovsky M, Musilova I, Bestvina T, Stepan M, Cobo T, Jacobsson B. Preterm Prelabor Rupture of Membranes between 34 and 37 Weeks: A Point-of-Care Test of Vaginal Fluid Interleukin-6 Concentrations for a Noninvasive Detection of Intra-Amniotic Inflammation. Fetal Diagn Ther. [2017 Epub ahead or print].

7. Musilova I, Andrys C, Drahosova M, Soucek O, Stepan M, Bestvina T, Spacek R, Jacobsson B, Cobo T, Kacerovsky M. Intraamniotic inflammation and umbilical cord blood interleukin-6 concentrations in pregnancies complicated by preterm prelabor rupture of membranes. J. Matern. Fetal. Neonatal Med. 30(8):900-910 (2017).


1. Sarvari SI, Rodriguez-Lopez M, Nuñez-Garcia M, Sitges M, Sepulveda-Martinez A, Camara O, Butakoff C, Gratacos E, Bijnens B, Crispi F. Persistence of Cardiac Remodeling in Preadolescents With Fetal Growth Restriction. Circ Cardiovasc Imaging. 10(1), e005270 (2017).

2. Guirado L, Crispi F, Masoller N, Bennasar M, Marimon E, Carretero J, Gratacós E, Martínez JM, Friedberg MK, Gómez O. Biventricular impact of mild to moderate pulmonary valve stenosis in fetal life. Ultrasound Obstet Gynecol. [2017 Epub ahead or print].

3. Valenzuela-Alcaraz B, Cruz-Lemini M, Rodríguez-López M, Goncé A, García-Otero L, Ayuso H, Sitges M, Bijnens B, Balasch J, Gratacós E, Crispi F. Fetal cardiac remodeling in twin pregnancies conceived by assisted reproductive technologies. Ultrasound Obstet Gynecol. [2017 Epub ahead or print].

4. Tanis JC, Mohammed N, Bennasar M, Martinez JM, Bijnens B, Crispi F, Gratacos E. Online versus offline spatiotemporal image correlation (STIC) M-mode for the evaluation of cardiac longitudinal annular displacement in fetal growth restriction. J Matern Fetal Neonatal Med. 1–6 (2017).

5. Gonzalez-Tendero A, Zhang C, Balicevic V, Cárdenes R, Loncaric S, Butakoff C, Paun B, Bonnin A, Garcia-Cañadilla P, Muñoz-Moreno E, Gratacós E, Crispi F, Bijnens B. Whole heart detailed and quantitative anatomy, myofibre structure and vasculature from X-ray phase-contrast synchrotron radiation-based micro computed tomography. Eur Hear J - Cardiovasc Imaging. 18(7):732-741 (2017).

6. Rodriguez-Lopez M, Wagner P, Perez-Vicente R, Crispi F, Merlo J. Revisiting the discriminatory accuracy of traditional risk factors in preeclampsia screening. PLoS One. 12(5):e0178528 (2017).

7. Schipke J, Gonzalez-Tendero A, Cornejo L, Willführ A, Bijnens B, Crispi F, Mühlfeld C, Gratacós E. Experimentally induced intrauterine growth restriction in rabbits leads to differential remodelling of left versus right ventricular myocardial microstructure. Histochem Cell Biol. 148(5):557-567 (2017).

8. Garcia-Canadilla P, Rodriguez JF, Palazzi MJ, Gonzalez-Tendero A, Schönleitner P, Balicevic V, Loncaric S, Luiken JJFP, Ceresa M, Camara O, Antoons G, Crispi F, Gratacos E, Bijnens B. A two dimensional electromechanical model of a cardiomyocyte to assess intra-cellular regional mechanical heterogeneities. PLoS One. 12(8):e0182915 (2017).

9. Sehgal A, Crispi F, Skilton MR, de Boode WP. Clinician performed ultrasound in fetal growth restriction: fetal, neonatal and pediatric aspects. J Perinatol. [2017 Epub ahead or print]

10. Rodriguez-Guerineau L, Perez-Cruz M, Gomez Roig MD, Cambra FJ, Carretero J, Prada F, Gómez O, Crispi F, Bartrons J. Cardiovascular adaptation to extrauterine life after intrauterine growth restriction. Cardiol Young. 1-8 (2017).

11. Valenzuela-Alcaraz B, Crispi F, Cruz-Lemini M, Bijnens B, García-Otero L, Sitges M, Balasch J, Gratacós E. Differential effect of assisted reproductive technology and small-for-gestational age on fetal cardiac remodeling. Ultrasound Obstet Gynecol. 50(1):63-70 (2017).

12. Miranda J, Triunfo S, Rodriguez-Lopez M, Sairanen M, Kouru H, Parra-Saavedra M, Crovetto F, Figueras F, Crispi F, Gratacós E. Performance of third-trimester combined screening model for prediction of adverse perinatal outcome. Ultrasound Obstet Gynecol. 50(5):603-611 (2017).

13. Miranda J, Rodriguez-Lopez M, Triunfo S, Sairanen M, Kouru H, Parra-Saavedra M, Crovetto F, Figueras F, Crispi F, Gratacós E. Prediction of fetal growth restriction using estimated fetal weight versus a combined screening model at 32-36 weeks of gestation. Ultrasound Obstet Gynecol. 50(3):353-360 (2017).

14. Rodríguez-López M, Cruz-Lemini M, Valenzuela-Alcaraz B, Garcia-Otero L, Sitges M, Bijnens B, Gratacós E, Crispi F. Descriptive analysis of different phenotypes of cardiac remodeling in fetal growth restriction. Ultrasound Obstet Gynecol. 50(2):207-214 (2017).

15. Ruiz A, Cruz-Lemini M, Masoller N, Sanz-Cortés M, Ferrer Q, Ribera I, Martínez JM, Crispi F, Arévalo S, Gómez O, Pérez-Hoyos S, Carreras E, Gratacós E, Llurba E. Longitudinal changes in fetal biometries and cerebroplacental haemodynamics in fetuses with congenital heart disease. Ultrasound Obstet Gynecol. 49(3):379-386 (2017).

16. Garcia-Canadilla P, Crispi F, Cruz-Lemini M, Valenzuela-Alcaraz B, Rudenick PA, Gratacos E, Bijnens BH. Understanding the Aortic Isthmus Doppler Profile and Its Changes with Gestational Age Using a Lumped Model of the Fetal Circulation. Fetal Diagn. Ther. 41(1):41-50 (2017).

17. Perez-Cruz M, Crispi F, Fernández MT, Parra JA, Valls A, Gomez Roig MD, Gratacós E. Cord Blood Biomarkers of Cardiac Dysfunction and Damage in Term Growth-Restricted Fetuses Classified by Severity Criteria. Fetal Diagn. Ther. [2017 Epub ahead or print].

18. Hernandez S, Moren C, Catalán-García M, Lopez M, Guitart-Mampel M, Coll O, Garcia L, Milisenda J, Justamante A, Gatell JM, Cardellach F, Gratacos E, Miro Ò, Garrabou G. Mitochondrial toxicity and caspase activation in HIV pregnant women. J Cell Mol Med. 21(1), 26–34 (2017).

19. Hernández S, Catalán-Garcia M, Morén C, García-Otero L, López M, Guitart-Mampel M, Milisenda J, Coll O, Cardellach F, Gratacós E, Miró Ò, Garrabou G. Placental Mitochondrial Toxicity, Oxidative Stress, Apoptosis And Adverse Perinatal Outcomes In Hiv-Pregnancies Under Antiretroviral Treatment Containing Zidovudine. JAIDS J Acquir Immune Defic Syndr. 75(4):e113-e119 (2017).

20. Arranz-Betegón Á, García M, Parés S, Montenegro G, Feixas G, Padilla N, Camacho A, Goberna J, Botet F, Gratacós E. A Program Aimed at Reducing Anxiety in Pregnant Women Diagnosed With a Small-for-Gestational-Age Fetus: Evaluative Findings From a Spanish Study. J Perinat Neonatal Nurs. 31(3):225-235 (2017).


1. Ortiz JU, Masoller N, Gómez O, Bennasar M, Eixarch E, Lobmaier SM, Crispi F, Gratacos E, Martinez JM. Rate and Outcomes of Pulmonary Stenosis and Functional Pulmonary Atresia in Recipient Twins with Twin-Twin Transfusion Syndrome. Fetal Diagn. Ther. 41(3):191-196 (2017).

2. Illa Armengol M, Eixarch E, Muñoz-Moreno E, Batalle D, Leal-Campanario R, Gruart A, Delgado-García JM, Figueras F, Gratacós E. Neurodevelopmental Effects of Undernutrition and Placental Underperfusion in Fetal Growth Restriction Rabbit Models. Fetal Diagn. Ther. [2017 Epub ahead of print]

3. Illa M, Brito V, Pla L, Eixarch E, Arbat-Plana A, Batallé D, Muñoz-Moreno E, Crispi F, Udina E, Figueras F, Ginés S, Gratacós E. Early Environmental Enrichment Enhances Abnormal Brain Connectivity in a Rabbit Model of Intrauterine Growth Restriction. Fetal Diagn. Ther. [2017 Epub ahead or print]

4. Jiménez JA, Eixarch E, Dekoninck P, Bennini JR, Devlieger R, Peralta CF, Gratacos E, Deprest J. Balloon removal after fetoscopic endoluminal tracheal occlusion for congenital diaphragmatic hernia. Am J Obstet Gynecol. 217(1):78.e1-78.e11 (2017).

5. Galindo A, Gómez-Montes E, Gómez O, Bennasar M, Crispi F, Herraiz I, Mendoza A, Escribano D, García-Torres E, Carretero JM, Gratacós E, Martínez JM. Fetal Aortic Valvuloplasty: Experience and Results of Two Tertiary Centers in Spain. Fetal Diagn Ther. [2017 Epub ahead of print]

6. Gumus HG, Illa M, Pla L, Gonzalez A, Demicheva E, Ley D, Crispi F, Gratacos E. Ultrasound-Guided Intrauterine Labeling of Rat Fetuses. Gynecol Obstet Invest. [2017 Epub ahead or print]

7. Bennasar M, Eixarch E, Martinez JM, Gratacós E. Selective intrauterine growth restriction in monochorionic diamniotic twin pregnancies. Semin Fetal Neonatal Med. pii: S1744-165X(17)30048-3 (2017).

8. Figueroa H, Alvarado C, Cifuentes J, Lozano M, Rocco J, Cabezas C, Illanes S, Eixarch E, Hernández-Andrade E, Gratacós E, Irarrazabal CE. Oxidative damage and nitric oxide synthase induction by surgical uteroplacental circulation restriction in the rabbit fetal heart. Prenat Diagn. 37(5):453-459 (2017).


1. Figueras F, Gratacos E. An integrated approach to fetal growth restriction. Best Pract Res Clin Obstet Gynaecol. 38, 48–58 (2017).

2. Figueras F, Gratacos E, Rial M, Gull I, Krofta L, Lubusky M, Rogelio C-M, Mónica C-L, Miguel M-R, Socias P, Aleuanlli C, Cordero MCP. Revealed versus concealed criteria for placental insufficiency in an unselected obstetric population in late pregnancy (RATIO37): randomised controlled trial study protocol. BMJ Open. 7(6), e014835 (2017).

3. Spencer R, Ambler G, Brodszki J, Diemert A, Figueras F, Gratacós E, Hansson SR, Hecher K, Huertas-Ceballos A, Marlow N, Marsál K, Morsing E, Peebles D, Rossi C, Sebire NJ, Timms JF, David AL, EVERREST Consortium. EVERREST prospective study: a 6-year prospective study to define the clinical and biological characteristics of pregnancies affected by severe early onset fetal growth restriction. BMC Pregnancy Childbirth. 17(1), 43 (2017).

4. Baranov A, Gratacós E, Vikhareva O, Figueras F. Validation of the prediction model for success of vaginal birth after cesarean delivery at the university hospital in Barcelona. J Matern Fetal Neonatal Med. 1–6 (2017).

5. Scazzocchio E, Crovetto F, Triunfo S, Gratacós E, Figueras F. Validation of a first-trimester screening model for pre-eclampsia in an unselected population. Ultrasound Obstet Gynecol. 49(2), 188–193 (2017).

6. Caradeux J, Eixarch E, Mazarico E, Basuki TR, Gratacos E, Figueras F. Second to third trimester longitudinal growth assessment for the prediction of SGA and late FGR. Ultrasound Obstet Gynecol. [2017 Epub ahead of print]

7. Basuki TR, Triunfo S, Caradeux J, Eixarch E, Hansson S, Gratacos E, Figueras F. Third-Trimester Conditional Reference Values for Longitudinal Fetal Growth Assessment. Fetal Diagn Ther. [2017 Epub ahead or print]

8. Caradeux J, Eixarch E, Mazarico E, Basuki TR, Gratacós E, Figueras F. Second- to Third-Trimester Longitudinal Growth Assessment for the Prediction of Largeness for Gestational Age and Macrosomia in an Unselected Population. Fetal Diagn Ther. [2017 Epub ahead or print]

9. Caradeux J, Eixarch E, Mazarico E, Basuki TR, Gratacos E, Figueras F. Longitudinal growth assessment for the prediction of adverse perinatal outcome in SGA-suspected fetuses. Ultrasound Obstet Gynecol. [2017 Epub ahead or print]

10. Borrell A, Grande M, Pauta M, Rodriguez-Revenga L, Figueras F. Chromosomal Microarray Analysis in Fetuses with Growth Restriction and Normal Karyotype: A Systematic Review and Meta-Analysis. Fetal Diagn Ther. [2017 Epub ahead or print]

11. Torres X, Bennasar M, Eixarch E, Rueda C, Goncé A, Muñoz M, Marimón E, Martínez JM, Gratacós E, Figueras F. Gender-Specific Antenatal Growth Reference Charts in Monochorionic Twins. Fetal Diagn Ther. [2017 Epub ahead or print]

12. Caradeux J, Martinez-Portilla RJ, Basuki TR, Kiserud T, Figueras F. Risk of fetal death in growth-restricted fetuses with umbilical and/or ductus venosus absent or reversed end-diastolic velocities before 34 weeks of gestation: a systematic review and meta-analysis. Am J Obstet Gynecol. pii: S0002-9378(17)32331-1 (2017).

13. Scazzocchio E, Oros D, Diaz D, Ramirez JC, Ricart M, Meler E, González de Agüero R, Gratacos E, Figueras F. Impact of aspirin on trophoblastic invasion in women with abnormal uterine artery Doppler at 11 − 14 weeks: A randomized controlled study (ASAP). Ultrasound Obstet. Gynecol. 49(4):435-441 (2017).

14. Borrell A, Grande M, Meler E, Sabrià J, Mazarico E, Muñoz A, Rodriguez-Revenga L, Badenas C, Figueras F. Genomic Microarray in Fetuses with Early Growth Restriction: A Multicenter Study. Fetal Diagn. Ther. 42(3):174-180 (2017).

15. Triunfo S, Crispi F, Gratacos E, Figueras F. Prediction of delivery of small for gestational age neonates and adverse perinatal outcomes by feto-placental Doppler at 37 weeks’ gestation. Ultrasound Obstet. Gynecol. 49(3):364-371 (2017).

16. Triunfo S, Crovetto F, Rodriguez-Sureda V, Scazzocchio E, Crispi F, Dominguez C, Gratacos E, Figueras F. Changes in uterine artery Doppler velocimetry and circulating angiogenic factors in the first half of pregnancies delivering small-for-gestational age neonates. Ultrasound Obstet. Gynecol. 49(3):357-363 (2017).

17. Crovetto F, Triunfo S, Crispi F, Rodriguez-Sureda V, Dominguez C, Figueras F, Gratacos E. Differential performance of first-trimester screening in predicting small-for-gestational-age neonate or fetal growth restriction. Ultrasound Obstet. Gynecol. 49(3):349-356 (2017).


1. Gómez Roig MD, Mazarico E, Ferrero S, Montejo R, Ibáñez L, Grima F, Vela A. Differences in dietary and lifestyle habits between pregnant women with small fetuses and appropriate-for-gestational-age fetuses. J Obstet Gynaecol Res. 43(7):1145-1151 (2017).

2. Gomez-Roig MD, Marchei E, Sabra S, Busardò FP, Mastrobattista L, Pichini S, Gratacós E, Garcia-Algar O. Maternal hair testing to disclose self-misreporting in drinking and smoking behaviour during pregnancy. Alcohol. [2017 Epub ahead or print]

3. Mazarico E, Llurba E, Cumplido R, Valls A, Melchor JC, Iglesias M, Cabero L, Gratacós E, Gómez-Roig MD. Neural injury markers in intrauterine growth restriction and their relation to perinatal outcomes. Pediatr Res. 83(3):452-457 (2017).

4. Sabra S, Gratacós E, Gómez Roig MD. Smoking-Induced Changes in the Maternal Immune, Endocrine, and Metabolic Pathways and Their Impact on Fetal Growth: A Topical Review. Fetal Diagn Ther. 41(4):241-250 (2017).

5. Sabra S, Malmqvist E, Saborit A, Gratacós E, Gomez Roig MD. Heavy metals exposure levels and their correlation with different clinical forms of fetal growth restriction. PLoS One. 12(10):e0185645 (2017).

Esta Web contiene información básica sobre distintos aspectos de la salud elaborada por profesionales y pacientes. Ofrece también recomendaciones y guías genéricas para el tratamiento de determinadas enfermedades por lo que, en ningún caso, debe ser utilizada para realizar diagnósticos, tratamientos médicos o cualquier actuación médica que deba ser realizada por un profesional sanitario. El contenido de la presente web no sustituye la atención personalizada de los equipos de salud. Queda totalmente prohibida la reproducción total o parcial de los contenidos de sin consentimiento expreso y por escrito por parte de Fundació Medicina Fetal Barcelona.

Last update: 09-Aug-2019 10:36 am